The GTG Server
Remote Homology Detection and Fold Assignment
The Global Trace Graph (GTG) is a pruned, all-against-all alignment graph of a non-redundant
representative set of all known protein sequences.
In this server, the concept of transitive alignment is used to trace paths through the graph between
your query protein and putative homologues via sets of intermediate neighbours. If any of these
homologues represent PDB structures, then folds can be assigned to your query protein. You can view
alignments between your query sequence and up to 50 best homologues, and will also be given a set of
links to various databases where you can view information about each homologue.
View help information by hovering your mouse-pointer over the input boxes or text. If you have javascript
disabled, you can view the entire help page «here».
SCOP: 1.71 | PDB: 13/02/2007 | Pfam-A: v21 | PairsDB: v2
Notes
Help Text: hover your mouse over the input boxes or text to see help on any of
the input options. If you have javascript disabled or the tooltips don't work, you can
open the entire help page «here».
You may like to use the ADDA interface to search
for your protein sequence if you have no luck here. ADDA always uses the most current version of
PairsDB, whereas the GTG may be based on an older version.
The sequence should be in plain (raw) or fasta format.
Whitespace and any numbers are okay as they will be stripped out.
If you have any comments about this server, you can send us a message by filling in the form
«here». Alternatively, use the email address at the bottom of the page.
Reference